Endocrine Abstracts

Introduction: Rutin (C27H30O16) is the major representative of the flavonol subclass of flavonoids. Rutin has wide variety of pharmacological activity, however there are not sufficient data in 3T3-L1 preadipocyte. In this study, we demonstrated that the effect of rutin on the proliferation of 3T3-L1 preadipocyte.Methods: The 3T3-L1 preadipocyte were treated with homocysteine (1 mM), rutin (30 μM) and rutin after homo...

Aim: An international expert committee, after considering data on association of HbA1c and retinopathy, recommended that diabetes be diagnosed when HbA1c is more than 48 mmol/mol (>6.5%), provided this assay is done in a standardized laboratory. However, the performance of HbA1c in detecting diabetes in the Korean population remains unknown. The purpose of this study was to evaluate the efficiency of HbA1c in diagnosing diabetes and to identify the optimal threshold in the...

Aim: HbA1c is recommended as a diagnostic criterion for diabetes in clinical practice guidelines for type 2 diabetes in 2011 (10). Although there have been several reports that compared HbA1c-based diagnosis for diabetes with glucose-based diagnosis in Koreans, it is thought that larger epidemiological studies are required to confirm the association of HbA1c and FPG for diagnosis of diabetes for the Korean population. We conducted this study to examine the relationship between...